Extended-Spectrum β-Lactamase–producing Enterobacteriaceae among Travelers from the Netherlands

نویسندگان

  • Sunita Paltansing
  • Jessica A. Vlot
  • Margriet E.M. Kraakman
  • Romy Mesman
  • Marguerite L. Bruijning
  • Alexandra T. Bernards
  • Leo G. Visser
  • Karin Ellen Veldkamp
چکیده

A prospective cohort study was performed among travelers from the Netherlands to investigate the acquisition of carbapenemase-producing Enterobacteriaceae (CP-E) and extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and associated risk factors. Questionnaires were administered and rectal swab samples were collected and tested before and after traveler return. Of 370 travelers, 32 (8.6%) were colonized with ESBL-E before trave,; 113 (30.5%) acquired an ESBL-E during travel, and 26 were still colonized 6 months after return. No CP-E were found. Independent risk factors for ESBL-E acquisition were travel to South and East Asia. Multilocus sequence typing showed extensive genetic diversity among Escherichia coli. Predominant ESBLs were CTX-M enzymes. The acquisition rate, 30.5%, of ESBL-E in travelers from the Netherlands to all destinations studied was high. Active surveillance for ESBL-E and CP-E and contact isolation precautions may be recommended at admission to medical facilities for patients who traveled to Asia during the previous 6 months.

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عنوان ژورنال:

دوره 19  شماره 

صفحات  -

تاریخ انتشار 2013